G037

G037 is a widely used narcotic analgesic medication, primarily for the management of moderate to severe pain. Manufactured by Tris Pharma Inc, this pill is available by prescription only. Its effectiveness and popularity are largely attributable to its double-action mechanism, which employs the opioid effect and the analgesic’s fever-reducing properties.

Ingredients

• Hydrocodone bitartrate 10 mg
• Acetaminophen 325 mg

These two medicines potentiate each other to provide maximum relief.

Description

It is identifiable by its unique physical characteristics. They are  white in color and oblong in shape, measuring approximately 16 mm in size. They have a descriptive alpha-numeric coding on one side, while the other side is creased for splitting in half. They are packaged in blister packs or bottles. Like most medications they should be stored in a dark, cool place.

Uses

They are primarily used as a powerful analgesic in the management of pain for a wide variety of applications, including:

• Management of moderate to severe pain that doesn’t respond well to non-opioid analgesics.
• Treatment of pain resulting from injury or trauma.
• Post-operative pain management.
• Pain relief in chronic conditions such as cancer.
• Management of persistent non-cancer related pain when other treatment options are inadequate.
• Management of moderate to severe dental pain, such as post-oral surgery or severe toothache.
• Treatment of back pain resulting from injury or chronic conditions such as arthritis or a herniated disc.
• Management of pain from sports-related injuries, such as sprains, fractures, or dislocations.

Peak Time

Upon oral administration, both components are readily absorbed in the gastrointestinal tract.

• Hydrocodone demonstrates peak plasma concentrations approximately 1.3 hours.
• Acetaminophen reaches peak levels within 0.5 to 2 hours.

Half-Life

The half-life of is approximately 3.8 hours. It is primarily metabolized in the liver, with less than 9% of the original dosage excreted unchanged in urine. Acetaminophen also undergoes hepatic metabolism, predominantly forming non-toxic compounds which are then eliminated in urine.

Dependency

This medicine is classified as a Schedule 2 controlled substance, possessing a significant risk of addiction and abuse. Hydrocodone is an opioid, so it can create physical dependence and withdrawal symptoms upon discontinuation after long-term use. 

Overdose

Overdose can occur if the medication is taken in larger amounts or for longer than prescribed, potentially leading to life-threatening conditions, including liver failure (from Acetaminophen) or respiratory depression and death.

Fact Sheet

download this fact sheet .pdf

image courtesy of drugs.com