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M367 Pill

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M367 is a white, oval pill. It is a generic prescription pain medication that combines the narcotic hydrocodone with the analgesic acetaminophen. The pill is embossed with an alphanumeric code for identification and has a crease down the middle for easy splitting. This combination increases the effectiveness of both components through a process called potentiation.

  • Upon ingestion, the effects typically peak within 15 to 20 minutes.
  • The duration of effectiveness ranges from four to eight hours.

Each tablet contains:

m367 pill


This medicine is commonly prescribed to treat various conditions  related to acute and moderate discomfort associated with:

  • back agony
  • post-operative recovery
  • dental procedures
  • migraines
  • arthritis
  • cancer

Containing an opioid narcotic, this medicine is used to manage severe discomfort that requires daily treatment. Healthcare professionals prescribe it for chronic agony management. It targets the receptors in the brain and is metabolized into morphine by the liver.

According to the Department of Justice (DOJ), hydrocodone is the most frequently prescribed opiate in the United States.


When it stimulates the receptors, it triggers the release of dopamine and serotonin, resulting in a euphoric and pleasant sensation. Prolonged abuse or long-term use can lead the brain to adapt to excess dopamine and serotonin, activating its reward centers. This can result in cravings when the levels of these neurotransmitters decrease.

It is important to note that this medicine can potentially interact with other substances. Please refer to the box warnings and additional details for information regarding potential interactions.

As tolerance builds over time, users may experience longer intervals for the drug to take effect, while the “come down” phase happens more quickly.

Other brand names include:

  • Vicodin
  • Lortab
  • Norco
  • Lorcet

Although acetaminophen is considered non-addictive, excessive use may lead to liver disease. This should be considered when using any product containing this drug, including over-the-counter meds.

Side Effects

Common side effects include:

  • constipation
  • nausea
  • vomiting
  • somnolence
  • headache
  • dizziness

More serious may include:

  • difficulty breathing
  • allergic reactions
  • rash
  • feelings of fear or anxiety
  • mood swings
  • inability to urinate
  • muscle tremors


Overdosing can occur, especially when time perception is altered. Users may lose track of the number of pills taken and the intervals between doses.

Signs of overdose include:

  • inability to stay awake
  • excessive perspiration
  • slowed or irregular pulse rate
  • shallow breathing
  • blood in the urine
  • chest pain
  • clammy skin

If an overdose is suspected, immediate medical assistance should be sought by calling 911.


There is a risk of addiction, abuse, and misuse even when taken at recommended doses. The dangers of overdose and potential death are significant, so extreme caution should be exercised when using this medicine.

The Drug Enforcement Administration (DEA) classifies it as a Schedule II narcotic controlled substance, with a DEA number of 9193. Individuals with a history of substance abuse are at high risk for misuse.

Treatment for addiction typically involves medical detoxification, psychological counseling, and medication. Abrupt withdrawal or quitting “cold turkey” can lead to potential health complications and should be avoided.

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