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Cyclobenzaprine High

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It is worth noting that people are often curious about getting high on Cyclobenzaprine. This medicine, a muscle relaxant often marketed under the brand name Flexeril, has been subject to abuse due to the incorrect perception that it can provide a euphoric effect. In this article, we will delve into the pharmacological aspects of this medicine, its recreational consumption, and the health consequences of such actions.


This drug has a well-established role in the realm of relaxants, especially in the treatment of spasms. Its primary application is to provide short-term relief from acute conditions. Here are its most common applications:

  • • Muscle spasms: It is often prescribed to manage contractions associated with painful musculoskeletal conditions. These Contractions could be due to an injury, an operation, or lower back pain or fibromyalgia.
  • • Adjunct to physical therapy: It is commonly applied in conjunction with rest and physical therapy to help relieve the symptoms. Its muscle-relaxing properties can be helpful in improving the overall efficacy.
  • • Off-label: There are some off-label (not FDA-approved) applications as well. These include the treatment of spasticity (persistent contractions) related to neurological issues, and as a sleep aid, due to its sedative effects.

It’s important to remember that using should always be guided by a healthcare professional. The duration is typically no longer than two to three weeks, and is not intended for long-term consumption. Prolonged ingestion may lead to dependence and possible side effects, and its effectiveness in providing sustained relief from contractions is not well studied beyond the recommended duration.


This medication is composed of both active and inactive ingredients. Here, we look at its composition, emphasizing that the actual contents may differ based on the pharmaceutical company that manufactures the product.

  • The active ingredient in the medication is cyclobenzaprine hydrochloride, a white, crystalline substance that is soluble in water and has a salty taste. 


This medicine is a central nervous system (CNS) muscle relaxant,  to treat twinges associated with severe musculoskeletal issues. It operates by blocking nerve impulses sent to your brain, thus easing tension. However, it is essential to understand that it doesn’t directly act on the tissue. Instead, it functions primarily within the central nervous system.

  • • It is not a narcotic, opioid, or benzodiazepine.
  • • It works within the central nervous system to provide muscle relaxation.
  • • This medicine is not directly linked with distortion or euphoria, unlike substances such as opioids.


Despite its legitimate therapeutic application, misuse occurs when it’s taken in a manner or dose other than prescribed, often to achieve a feeling of euphoria. It’s important to note that the sensation often associated with recreational use is not the typical euphoria experienced with substances like opioids or benzodiazepines.

  • This is often associated with sedation and drowsiness rather than euphoria.
  • Taking the drug in higher doses than recommended can lead to dangerous side effects.
  • Combining it with other substances, such as alcohol or benzodiazepines, can result in potentially lethal outcomes due to increased CNS depression.

Health Concerns

Misuse can lead to severe health consequences. Potential risks and side effects include:

  • • CNS depression: Overdose can result in life-threatening respiratory distress or even coma.
  • • Serotonin syndrome: When combined with other substances that increase serotonin levels, such as certain antidepressants, there is a risk of serotonin syndrome, a potentially fatal condition.
  • • Dependency and withdrawal: While this medicine is not typically associated with physical addiction, psychological dependence can occur, and abrupt discontinuation may lead to withdrawal symptoms.
  • • Cardiac complications: Overdose may lead to a rapid heart rate, high or low blood pressure, and even cardiac arrest.

While this medicine serves a crucial role in managing twinges related to acute conditions, abusing it can lead to significant health consequences, most of which are far from the euphoria sought by some people. It’s imperative to understand that the perceived “buzz” is often misinterpreted as sedation and drowsiness, which can escalate into life-threatening situations in cases of overdose or when combined with other substances. It’s crucial always to manage this medication as directed by a healthcare provider to avoid these potentially dangerous outcomes.