Skip to content

Wellbutrin and Alcohol

Taking Wellbutrin and drinking alcohol can cause health and drug-related problems. Wellbutrin® is a common anti-depressant. A daily medication to combat depressive symptoms of this mood disorder.

Some people combine these two drugs for the effects they can have for social or recreational purposes. Because of this, it’s common for people taking these drugs to know the possible side effects and risks. Doctors should always remind patients when prescribing it not to drink.

  • Click to see the actual warnings on the box.

Several factors make this combination of drugs and alcohol very risky. Due to this, the exact consequences will differ for each person. However, because combining these two drugs can result in serious illness, and there is no way to determine the implications for any individual, all people should avoid drinking while taking this drug.

This combination is primarily dangerous because they are both CNS-active compounds. Because both compounds act on the central nervous system, increasing the other’s intensity or effects. In layman’s terms, this means that Wellbutrin makes the effects of drinking more potent and vice versa.

  • The effects of alcohol increase by the fact Wellbutrin reduces alcohol tolerance.

Because of this, individuals drinking and on Wellbutrin will suffer from the effects of alcohol after consuming less alcohol than usual, and those effects will be stronger than average.

In addition to heightening the side effects, mixing this drug with alcohol results in another problem because Wellbutrin is an antidepressant and alcohol is a depressant.

When both compounds are in the system, they cancel each other out. As a result, people who mix these are likely to experience an episode of depression. In the worst-case scenario, this can lead to serious self-harm.


One of the most severe side effects of Wellbutrin is seizures. Therefore, doctors who prescribe this drug are usually cautious with dosage to minimize this side effect and won’t prescribe it to people already in danger of a seizure.

Side effects

The side effects increase like all the others when combining these two drugs. In addition, it is hazardous because most people prescribed this drug are not familiar with dealing with the effects, which means that a sudden episode can result in serious injury due to a lack of familiarity.

Here is a list of some of the side effects:

  • Seizures
  • Dizziness
  • Blackouts
  • Nausea
  • Vomiting
  • Confusion
  • Impaired judgment
  • Paranoia
  • Overdosing

Call 911 immediately at the first signs of an overdose.

As with all overdoses, medical attention is critical. An overdose can result in severe repercussions such as organ damage, coma, or worse.

As previously noted, because both compounds increase the strength of each other, it is possible to overdose on Wellbutrin or alcohol, or both at the same time. Even if only on the prescribed dosage and only modest amounts of alcohol have been consumed.