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Tranxene: Addictive, Long-Lasting Benzodiazepine


Tranxene (generic name Clorazepate) is a benzodiazepine possessing sedative, hypnotic and anxiolytic properties. It exerts powerful, long-lasting, anti-anxiety and muscle relaxant effects. Desmethyldiazepam is responsible for most of the therapeutic effects of clorazepate.

  • In fact, the combination of alcohol and this drug could cause users to stop breathing or become comatose.

The U.S. Drug Enforcement Agency designates this drug and other benzodiazepines as a Schedule IV controlled substance available only through a physician’s prescription. Buying or selling Tranxene on the street is illegal and an arrestable offense.

Clorazepate is primarily prescribed for treating:

  • epilepsy
  • alcohol withdrawal syndrome
  • relieve chronic anxiety
  • insomnia
  • severe muscle spasms


Typical doses of Clorazepate for anxiety can generally be around 30 mg per day for adults depending on a variety of variables. (only as prescribed by a doctor). This is NOT medical advice.

How It Works

Like other benzodiazepines and alcohol, Clorazepate increases efficiency of transmitting the neurotransmitter GABA by stimulating GABA receptors to bond more effectively with benzodiazepine molecules. Tranxene binds readily to blood proteins and will cross over into breast milk and the placenta.

How Long To Take Effect

Within 30 to 120 minutes of taking Clorazepate, users generally feel its effects as the drug reaches peak plasma levels.

Side Effects

Common side effects of taking 30 mg of Clorazepate might include:

  • Drowsiness/sleepiness
  • Euphoria
  • Dizziness
  • Blurry vision
  • Dry mouth
  • Reduced motor and cognitive functioning

Some Clorazepate users report paradoxical effects, such as feeling excited and hyperactive. Other adverse effects reported are confusion, hangover-like symptoms, amnesia and depression.


People who take life-threatening overdoses of Clorazepate are usually addicted to the drug and must take higher doses to feel its sedative effects.  An overdose may also happen when the user forgets how much Clorazepate they have taken.

  • People should never take more than 90 mg of Clorazepate in a 24 hour period.

Signs of overdosing on Clorazepate include:

  • Inability to remain conscious
  • Reduced respiratory and heart rates
  • Difficulty breathing/slow breathing
  • Slurred speech
  • Confusion/delirium

Coma and death may result if a Clorazepate overdose is not treated immediately with supportive medical procedures such as gastric suction (stomach pumping), fluid replacement and intubation.

Mixing With Alcohol

Combining alcohol with Clorazepate will intensify the effects of both drugs and put users at an increased risk of suffering life-threatening symptoms.

  • In fact, the combination of alcohol and Clorazepate could cause users to stop breathing or become comatose.

Since alcohol and benzodiazepines both depress the central nervous system, mixing Clorazepate and alcohol will induce extreme sedation and dangerously slow breathing by acting on glutamate and GABA receptors.

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