IP 109 – IP 110 – IP 115: Generic Opioid Painkillers Plus POTENTiator

ip109-110 label

IP 109, IP 110 and IP115 are white, capsule-shaped tablets embossed with these letters and numbers. Each tablet contains a combination of hydrocodone bitartrate, an opiate narcotic pain killer and acetaminophen (Tylenol).

  • They are prescribed to relieve moderate to severe pain such as back pain or rheumatoid arthritis.

The combination of hydrocodone bitartrate and acetaminophen potentiate each other, meaning they produce additive pain relief, as compared to either hydrocodone or acetaminophen separately.

  • They’re considered a narcotic-analgesic combination drug
  • The generic name is hydrocodone-acetaminophen
  • Some brand names include Lortab® and Norco®

All contain the same ingredients in different quantities, as follows:

IP 109

  • 5 mg hydrocodone
  • 325 mg acetaminophen

IP 110

  • 10 mg hydrocodone
  • 325 mg acetaminophen

IP 115

  • 7.5 mg hydrocodone
  • 325 mg acetaminophen

For more variations of this formulation, hover here.


A single tablet contains either 5 mg, 7.5 mg or 10 mg of hydrocodone and 325 mg of acetaminophen. A typical health-care provider’s prescription might call for 1 to 2 tablets every 4 to 6 hours as needed, not to exceed 12 tablets per day.

Side Effects

Side effects may be more likely and serious in older adults. Long-term use of medication that contain opioids, may affect the ability to have children in both men or women. Those child-bearing effects may or may not be permanent.

  • Lightheadedness
  • Dizziness
  • Anxiety
  • Nausea and vomiting
  • Upset stomach
  • Drowsiness
  • Constipation
  • Headache
  • Mood changes
  • Blurred vision
  • Tinnitus (ringing in your ears)
  • Dry mouth
  • Difficulty urinating


These pills can slow or stop the ability to breathe and can be habit-forming. If improperly used, it can trigger addiction, overdose, or death, especially in a child or elderly person or a person using them without a prescription.

These medication MUST be kept out of the reach of the reach of children and pets as accidental exposure may cause respiratory failure and a fatal overdose.

According to Medlineplus “When a hydrocodone combination product was used in children, serious and life-threatening breathing problems such as slow or difficulty breathing and deaths were reported. Hydrocodone should never be used to treat pain … in children younger than 18 years of age.”

Since hydrocodone can affect the ability to breathe properly, the additive effect of taking other medications simultaneously or drinking alcohol can have serious effects.

  • Healthcare providers and pharmacist should be made aware of what prescription and nonprescription medications  someone is taking or plan to take while on these meds.

These drugs carry this warning as well …”may impair the mental or physical abilities needed to perform potentially hazardous activities such as driving a car or operating machinery.


There is long list of possible drug interactions. Other medications may also interact with hydrocodone combination products, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.

This medication should not be used with any of the following medications:

  • Nalmefene
  • Naltrexone
  • Safinamide
  • Tylenol

Speak to a healthcare provider or the pharmacist before taking these medications. Here is a list of some of the possible interactions if you have asthma or COPD.

  • taking depressants (sedatives, tranquilizers, hypnotics (i.e.sleeping pills)
  • heart health issues
  • over-weight problems
  • pulmonary disease
  • respiratory depression
  • respiratory insufficiency
  • scoliosis
  • sleep apnea
  • extreme asthma

By The Letters and Numbers

The Food and Drug Administration (FDA) states that all solid oral dosages drugs must be: “…clearly marked or imprinted with a code imprint that, in conjunction with the product’s size, shape, and color, permits the unique identification of the drug product and the manufacturer or distributor of the product.” The FDA suggests: “Inclusion of a letter or number in the imprint, while not required, is encouraged …”

National Drug Codes (NDC)

The NDC, or National Drug Code, is a unique 10-digit, 3-segment number. It is a universal product identifier for human drugs in the United States NDC.


Possible Container Sizes


All three of these medications contain hydrocodone (a Schedule II narcotic) users are exposed to the possibility of addiction, abuse, and misuse.

Hydrocodone is a Schedule II controlled substance, meaning it:

  • Has a high potential for abuse.
  • Is currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions.
  • If abused the drug may lead to severe psychological or physical dependence.


Any overdose can be fatal. Signs of a possible overdose on these drugs include:

  • Slow and ineffective breathing
  • Sleepiness or drowsiness progressing to stupor or coma
  • Skeletal muscle flaccidity
  • Cold and clammy skin
  • Pupils unusually small under normal light

In some cases, early overdose symptoms may include:

  • Nausea
  • Vomiting
  • Excessive, abnormal sweating in relation to the environment and general malaise
  • Clinical and laboratory evidence of liver toxicity may not be apparent until 48 to 72 hours post-ingestion


Acetaminophen has been shown to be associated with liver failure, alcoholism, ethanol intoxication, hepatitis, liver damage and malnutrition.



Complete Detailed – Reference Sheet (NIH)