How Long Can Someone Expect The Effects Of Adderall To Last

Adderall is an amphetamine prescribed for attention deficit hyperactivity disorder and narcolepsy.

Adderall stimulates the central nervous system by forcing the brain to release extra norepinephrine, dopamine, and adrenaline, three neurotransmitters implicated in the “fight or flight” response humans rely on to survive stressful situations.

  • College students and athletes take Adderall for its ability to increase both physical and mental alertness.

There are two basic types of Adderall available at the pharmacy today.

  • Immediate release Adderall IR, some users may not need to take more Adderall IR for 6 to 8 hours, while others may need to take another dose of Adderall after 12 hours.
  • Extended-release Adderall XR should last 24 hours and only taken once per day.
  • A user’s length feels these effects depend on individual variables such as physical activity, metabolism, dietary intake, and body chemistry.
  • After administering a single dose of 10 or 30 mg of ADDERALL® to healthy volunteers under fasted conditions, peak plasma concentrations occurred approximately 3 hours post-dose for both d-amphetamine and l-amphetamine.

Adderall XR

Adderall XR is an oral medication providing relief from ADHD or narcolepsy symptoms for 24 hours. This form of Adderall contains ingredients that allow beads in capsules to release amphetamines in “pulses.” Parents of children with ADHD find extended-release Adderall more convenient than twice or three times a day Adderall.

Adderall has a half-life (the time it takes for Adderall to lose 50 percent of its strength) will depend on urine pH when urine is normal or slightly lower than average pH. The more acidic someone’s urine is the lower Adderall’s half-life. Nearly 40 percent of Adderall is eliminated primarily by the kidneys. Abnormal urine pH levels could expand recovery ranges of Adderall in the urine by as much as one to 75 percent.

  • Adderall’s half-life is about 10 hours.

According to the FDA, “The mean elimination half-life (t1/2) for d-amphetamine was shorter than the t1/2 of the l-isomer (9.77-11 hours vs. 11.5-13.8 hours)”

Adderall’s absorption rate by the body and accessibility is called bioavailabilityThe main factor influencing the bioavailability of Adderall is the pH level of the gastrointestinal system. The gut absorbs the more acidic the system, the less Adderall. Following ingestion of Adderall, between15 to 40 percent of the drug circulates in the bloodstream, where it binds to plasma proteins. Adderall goes into most of the body’s soft tissues. Peak bioavailability, with higher brain tissue and cerebrospinal fluid concentrations.

The effects generally start within one hour of taking a standard dose. Most people taking Adderall will feel its effects that include:

  • increased energy
  • better focus
  • improved mood
  • control behavior
  • pay attention

Euphoria and a sense of omnipotence are other side effects of Adderall. Withdrawal symptoms such as cravings, insomnia, panic attacks, heart palpitations, depression, and suicidal thoughts will impact those who are addicted to Adderall and have developed a high tolerance for the drug. When Adderall stops increasing neurotransmitter levels in the brain, users may experience the rapid onset of;

  • extreme fatigue
  • weakness
  • irritability
  • anxiety
  • hunger
  • depression
  • inability to concentrate

The side effects of Adderall may worsen for several days and then slowly decrease over two to three weeks. Depending on how long an Adderall abuser has been taking the drug and how much they take daily, withdrawing from Adderall can require professional intervention to avoid relapsing. Severe withdrawal symptoms include nausea, vomiting, dehydration, muscle tremors, and panic attacks. However, there is no medication to help with Adderall withdrawal, seek medical and psychological support.