Mixing Gabapentin And Alcohol

Wondering what happens when Gabapentin and alcohol are combined?

Gabapentin is an anticonvulsant agent that is primarily used to treat seizures and occasionally prescribed to treat nerve pain caused by shingles. Like many prescription drugs, alcohol is contraindicated while taking Gabapentin, which means that alcohol is likely to limit the effectiveness of the drug or that the combination of the two is likely to result in dangerous side effects.

Gabapentin And Alcohol

Despite being contraindicated, it is quite common for people taking Gabapentin to be interested in consuming alcohol. This interest has resulted in a small community that intentionally mixes the two drugs in order to enjoy the high and side effects that results. Like any prescription abuse, this is a dangerous course of action that can potentially result in hospitalization or maybe worse.

Alcohol and Gabapentin Potentiation

Alcohol and Gabapentin are drugs that potentiate each other. This means that when the drugs interact in the human body, they each increase the effects caused by the other drug. For alcohol, this means that the alcoholic high is stronger and kicks in with less alcohol. It also means, for both drugs, that unfortunate side effects common with these drugs are equally heightened.

Consequences of Mixing Gabapentin With Alcohol

The good news about mixing Gabapentin and alcohol is that, unless a person overdoses on one or both, it is unlikely that the combination will kill them. And while overdosing is easier when combining the drugs than when taken separately, it still is reasonably unlikely. That does not, however mean that mixing the drugs is safe.

While death is an extremely rare consequence, hospitalization is highly likely for other reasons. The most common reason is due to injury from a fall. Alcohol is a depressant that decreases motor functions and responsiveness. Gabapentin also decreases motor functions via direct action on the nervous system. As a result, people who take both drugs are highly likely to fall from even simple movements and are unlikely to have the motor skills to brace for such a fall successfully.

List Of Consequences

Falling is just one of the many possible consequences that can arise from the following side effects that are heightened when mixing these drugs:

  • Loss of coordination
  • Extreme drowsiness
  • Dizziness
  • Confusion
  • Loss of memory
  • Blurred vision
  • Dry mouth
  • Nausea
  • Vomiting

When magnified, these side effects create a generally unsafe situation, especially if the person is engaging in any activity that involves vehicles or exercise. This safety hazard extends both to the person mixing the drugs and to individuals in the vicinity.

  • Anyone who has drunk alcohol while taking Gabapentin should call 911 or go to urgent care. Otherwise, immediately find a safe place to sit or lie down until the effects of the drugs have passed.

Treatment For Alcohol and Gabapentin Abuse

There is an additional reason, besides intentional abuse, that alcohol is heavily associated with Gabapentin. Some researchers have discovered that Gabapentin may be an alternative option to benzodiazepines for assisting with alcohol withdrawal. Because the drug potentiates alcohol, it can allow alcoholics to drink less alcohol while feeling roughly the same effects, helping to detoxify the alcohol from their system.

In a controlled setting like a comprehensive alcohol rehabilitation program, this mixture is safe and actually beneficial. However, just because it is safe in this very limited situation, that doesn’t mean that it can be considered safe generally. While doctors may have the knowledge and tools to safely and beneficially mix the two drugs, the average person doesn’t and should avoid doing so at all costs.


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