AN 627 are round, white, coated pills containing Tramadol Hydrochloride. Tramadol is an opioid analgesic drug prescribed by physicians to relieve acute or chronic pain. Extended-release versions provide rapid pain relief within 30 to 60 minutes. Sometimes drowsiness, sedation, and dizziness occur before the pain decreases. How well people tolerate this drug is determined primarily by their age, weight, health, and other factors.
- Pain-relieving medications naturally make a person more relaxed and capable of falling asleep once pain subsides.
- An 627 are available in 50 mg doses only.
It is the opioid affecting receptors that control pain sensations, sedation, and to some extent, mood. As a result, some people may doze off for a short time using tramadol, while others could lapse into a lengthier sleep.
Tramadol provides pain relief similar to the effectiveness of morphine for moderate pain. However, it is not as effective as morphine for severe pain. Therefore, doctors may prescribe both tramadol and acetaminophen to alleviate severe pain. It is available by prescription only in tablet, liquid, and capsule form.
Physicians prescribe tramadol for moderate pain usually between 50 mg and 100 mg. The maximum tramadol dose is 400 mg per day. Exceeding this dosage could cause serious side effects and signs of an overdose.
Extended-release tramadol is a 100 mg tablet taken once daily. The maximum dose of extended-release tramadol should not exceed 300 mg per day..
There are multiple warnings and contraindications for this drug; see details. Users must tell their doctor if they take antidepressants, anxiety medication, other opioids, amphetamines, or antibiotics. Interaction between Tramadol and any of these drugs could cause adverse side effects requiring emergency medical treatment.
Mixing this drug with alcohol is dangerous and increases the intensity and accelerates the side effects. According to the government’s website Medline, “Drinking alcohol while taking prescription or nonprescription medications that contain alcohol, or using street drugs during your treatment can be dangerous.”
Drinking alcohol while on tramadol increases the risk of experiencing the serious, life-threatening side effects listed below. Therefore, do not drink alcohol, take prescription or nonprescription medications that contain may alcohol. Also, do not use street drugs during AN 627 treatment.
Since An 627 is an opioid pain reliever, users will experience side effects similar to other opioid analgesics. Side effects can include:
- mental fog
- decreased alertness
- body numbness
Other adverse side effects could include the following:
- Nausea and vomiting
- Dry mouth
- Stomach cramps
Tramadol can also act as an antidepressant because it keeps higher serotonin and norepinephrine levels in the brain. Also, Tramadol binds to opioid receptors like morphine and heroin to induce intense pain relief.
The liver further converts tramadol into a potent opioid called desmetramadol. Desmetramadol is a legal substitute for street and pharmaceutical opioids. A blend of synthetic desmetramadol and Kratom goes by “Krypton.” Unfortunately, Krypton has been the cause of several overdose deaths in the past few years.
As an opioid, abuse and addiction are serious concerns. Tramadol is a controlled substance listed by the DEA as Schedule IV. The following statistics are per the National Survey on Drug Use and Health for 2016;
- 1.6 million people in the U.S. aged 12 or older misused tramadol products in the past year.
Tramadol is a popular prescription medication. According to the DEA;
- 43.6 million tramadol prescriptions in the U.S. in 2016.
- 16.0 million prescriptions in the first half of 2018.
The “AN” portion comes from the manufacturer’s name, Amneal Pharmaceuticals. So, the AN is an acronym for AmNeal. The “627” comes from the National Drug Code (NDC) (see below).
The National Drug Code NDC is a directory of all drugs sold in the U.S. Here are the NDC codes for AN627 and their contents.
|65162-627-01||10 tablets per bottle|
|65162-627-10||100 tablets per bottle|
|65162-627-11||1,000 per bottle|
|65162-627-50||500 per bottele|