Amoxicillin And Alcohol – Drinking Alcohol While On Amoxicillin

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In case you’re wondering whether it ok to mix Amoxicillin and alcohol? If you have ever been prescribed Amoxicillin, you have probably noticed the warning label on the side of the bottle that reads something like “Do not take in combination with alcohol.” Because Amoxicillin and other penicillin derivatives are the most common form of antibiotic prescribed for infections in the United States, most people have seen this warning at least once. Due to the significant number of warnings that appear on drug labels these days, patients commonly ask whether this particular warning is a legitimate concern or whether it is overstated.

Can You Drink Alcohol While Taking Amoxicillin?

If the question is whether Amoxicillin will cause death when mixed with alcohol, the answer to that question is a resounding “no.” Both Amoxicillin and alcohol use can independently result in death, especially when taken in excess or when the patient has an unknown allergy to penicillin derivatives, but the combination of the two drugs does not meaningfully increase that risk.
However, death isn’t the only risk associated with combining alcohol and Amoxicillin. Another major risk is a decrease in effectiveness of the Amoxicillin in treating the infection it was prescribed for. This risk derives from the fact that the same enzymes are used to break down both penicillin based drugs and alcohol in the blood stream. When too much alcohol is in the blood stream, it inhibits those enzymes, slowing down the rate at which penicillin derivatives are broken down, resulting in decreased effectiveness of the drug and drug toxicity.

Side Effects Of Mixing Amoxicillin and Alcohol

Due to both drug toxicity and standard interactions between the two types of drugs, numerous side effects are common when alcohol and Amoxicillin are used at the same time.

  • These side effects include:• Vomiting, nausea, and diarrhea
  • Dehydration, often resulting from the above side effect and exacerbated by alcohol
  • Headaches
  • Flushed skin
  • An increased heart rate which can also lead to difficulty breathing
  • Chest pain, possibly resulting from difficulty breathing.

Besides being unpleasant, these side effects put a further strain on the body, which hinders the healing process by forcing the body to spend resources dealing with these side effects, rather than healing the infection. It is unlikely to be life threatening, but it will increase the time it takes for you to fully heal from whatever malady that the Amoxicillin was prescribed for in the first place.

How Much Alcohol is Too Much?

Doctors universally agree on the answer to this question.

  • Any amount of alcohol, even as little as a single glass of wine, is too much while you are on any antibiotic, including Amoxicillin.

Dehydration and nausea kick in almost as soon as any amount of alcohol enters the system and these two side effects produce a high toll on the body and the ability to heal.

Doctors recommend that patients simply avoid any alcohol while taking antibiotics. In particular, because antibiotics are often prescribed for infections that produce cold-like symptoms, patients should carefully read the labels of over-the-counter medicines to be certain that they don’t include any alcohol. And for the roughly 5% of patients in the United States that are active alcoholics, the best way to avoid a prolonged and unpleasant healing process is to inform your doctor of your alcoholism when the antibiotic is prescribed. This will allow your doctor to help you safely take the medicine.




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